You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider.

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about topical Spiroxidil™:

• Spiroxidil™ is a compounded medication combining topical Spironolactone and topical Minoxidil, as well as cetirizine, caffeine and melatonin.
• Spironolactone is primarily a medication used to treat conditions like high blood pressure and fluid retention (edema) due to its diuretic effects. Topical Spironolactone is sometimes used off-label for its  anti-androgenic effects in the treatment of hair loss, particularly in women who have a condition called androgenetic alopecia (female pattern hair loss) or other hair loss conditions with an androgenic component. 
• Topical Minoxidil is FDA-approved for the treatment of hair loss, including androgenetic alopecia. 
• Cetirizine, Caffeine and Melatonin are compounded together to be used off-label as supportive topicals aiding in promoting blood flow, a better scalp environment, slowing further hair loss, and improving hair growth.

Absolute Contraindications – DO NOT use Spiroxidil™ if you: 

• Are allergic to any of the active ingredients
• Are under 18 or are pregnant, breastfeeding, or planning to become pregnant 
• Have any present or past cancer, heart problems, kidney problems or liver problems
• Have high/low blood pressure or orthostatic hypotension
• Have any present or past issues with hyperkalemia, Addison's disease (chronic adrenal insufficiency), or other conditions associated with hyperkalemia and or are receiving other potassium-sparing agents. 

Drug Interactions – DO NOT use Spiroxidil™ if you take: 

• ACE inhibitors
• angiotensin receptor blockers
• Potassium channel blockers or medications for hyperkalemia
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Diuretics
• Trimethoprim
• Lithium
• Cholestyramine
• Abiraterone
• Digoxin
• Eplerenone
• Alfentanil
• Alprazolam
• Buprenorphine
• Opioids
• Trimethoprim
• Lithium
• Guanethidine
• Certain blood pressure medications and certain hepatic/ liver medications or medications for Addison’s disease (see a doctor in-person about seeking treatment with Spiroxidil™)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Chest pain, rapid heartbeat, faintness, dizziness, shortness of breath or difficulty breathing  
• Hypotension (low blood pressure) 
• Sudden, unexplained weight gain (edema)
• Swelling in the hands, legs, feet or ankles
• Worsening of renal (kidney) or hepatic (liver) function
• Digestive abnormalities including bleeding and vomiting 
• Electrolyte and metabolic abnormalities
• Severe scalp irritation 
• Increase in potassium (hyperkalemia)
• Gynecomastia/breast tenderness/increase in breast size
• Impaired neurological function 
• Stevens-Johnson Syndrome (SJS)

It’s important to closely and regularly monitor for these side effects while taking Spiroxidil™, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop using Spiroxidil™ and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Unwanted hair growth on the face or body
• Headache   
• Scalp irritation, including redness and itching
• Insomnia, nausea, dry mouth
• Hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Some may also experience changes in hair texture and color. 

These are not all the possible side effects of Spiroxidil™. For more information, ask your healthcare provider or pharmacist and refer to the complete prescribing information: Spironolactone, Topical Minoxidil, Cetirizine, Topical Melatonin, Caffeine

SERIOUS WARNINGS:

• PREGNANCY RISK: Spironolactone, one of the active ingredients in Spiroxidil™ may cause birth defects based on its mechanism and animal studies. Pregnant women and women who plan to become pregnant in the near future, should not take spironolactone under any circumstances.

Do not let children, pregnant or breastfeeding women, or women who may become pregnant handle this medication. Do not let them touch the area where the medication is applied (scalp). If contact occurs, they should immediately wash the affected skin area with soap and water.

• POSSIBLE INFERTILITY RISK: Spironolactone, one of the active ingredients in Spiroxidil™ may cause an increased risk of  infertility, breast tenderness/increase in breast size, irregular periods, or lack of menstrual periods. If you notice these symptoms, seek immediate emergency medical care. 
• POSSIBLE CANCER RISK: Spironolactone, one of the active ingredients in Spiroxidil™, may cause an increased risk of certain types of cancer.  During animal testing, orally administered spironolactone caused tumor growth in specific rats. Although animal findings don't always reflect human responses, Tangl dermatologists adhere to a principle of caution when prescribing. Due to its potential carcinogenic implications, you should not use Spiroxidil™ if you have a history or risk of cancer. If you notice any unusual symptoms, seek immediate emergency medical care. 
• POSSIBLE CARDIAC RISK: In rare cases topical minoxidil, one of the active ingredients in Spiroxidil™, can lead to cardiovascular side effects. Pericardial effusions, which is the excessive buildup of fluid in the sac surrounding the heart (pericardium), have been reported in patients taking minoxidil. This can progress to cardiac tamponade, which is a life-threatening condition where the fluid pressure compresses the heart, preventing it from effectively pumping blood. Symptoms encompass sharp chest pain and breathing difficulties. If you notice these symptoms, seek immediate emergency medical care.

Always use Spiroxidil™ under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

WARNING: TOXIC TO ANIMALS

• Minoxidil, one of the active ingredients in Spiroxidil™, is highly toxic to animals, especially cats; even trace amounts can be life-threatening. 
• Do not apply minoxidil if pets are in close proximity
• Do not approach your pets until the treated area has thoroughly dried
• Wash hands and surfaces thoroughly after application
• Do not let pets near the application site (i.e. do not hold pets near your face/hair)
• Beware of pillowcases: minoxidil can transfer to pillow cases during sleep. To prevent any risk to your pets, especially cats, consider removing or replacing pillow cases after use. Alternatively, ensure that your pets do not have access to areas where pillows might be.
• Always store Spiroxidil™ in a secure location out of reach of pets. 
• Always store Spiroxidil™ in a secure location out of reach of pets. 
• If you suspect your pet has come into contact with minoxidil or displays symptoms such as lethargy, rapid breathing, vomiting, or collapse, seek emergency veterinary care immediately.

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Instructions For Use:

• Follow your healthcare provider's specific instructions when using this medication
• Do not apply this medication more than the recommended dose; doing so won't enhance results and may raise the likelihood of side effects.
• Wash your hands with soap after application
• This product is meant solely for your scalp, repeated contact with other skin areas can potentially result in unwanted hair growth. If the medication accidentally gets on your face, wash it off with soap and water immediately.
• Do not apply on other parts of the body
• Avoid contact with the eyes. In case of accidental contact, rinse eyes with copious amounts of cool tap water. 
• Do not use this medication for a condition for which it was not prescribed.
• Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Storage Information

• Keep this medication at a room temperature 
• Dispose of the medication if you are no longer using it. 
• Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is not comprehensive. Please see the full prescribing link below for complete safety information: Spironolactone, Topical Minoxidil, Cetirizine, Topical Melatonin, Caffeine

You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider. 

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about topical Finoxidil™: 

• Finoxidil™ is a compounded medication combining topical Finasteride and topical Minoxidil, as well as cetirizine, caffeine. 
• Finasteride is an FDA-approved medication used to treat male pattern baldness due to its DHT blocking effects. Low dose topical finasteride is sometimes used off-label for its anti-androgenic effects in the treatment of hair loss, particularly in women who have a condition called androgenetic alopecia (female pattern hair loss) or other hair loss conditions with an androgenic component. It works by inhibiting the activity of the hormone dihydrotestosterone (DHT), which is a key factor in hair loss in individuals with a genetic predisposition to this condition. 
• Topical minoxidil is a widely used medication for the treatment of hair loss, including androgenetic alopecia. 
• Tretinoin and melatonin are compounded together to be used off-label as supportive topicals aiding in better absorption of the ingredients, creating an optimized scalp environment, and improving the hair growth cycle.

Absolute Contraindications – DO NOT use Finoxidil™ if you: 

• Are allergic to any of the active ingredients
• Are pre-menopause or are pregnant, breastfeeding, or planning to become pregnant. Finoxidil™ is made for post-menopausal women only.
• Have any present or past cancer, heart problems, kidney problems or liver problems

Drug Interactions – DO NOT use Finoxidil™ if you take: 

• Lithium
• Guanethidine
• Saw Palmetto 
• Certain blood pressure medications (see a doctor in-person about seeking treatment with Finoxidil™) 

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Chest pain, rapid heartbeat, faintness, dizziness, or difficulty breathing  
• Sudden, unexplained weight gain (edema)
• Swelling in the face, hands, legs, feet or ankles
• Tingling or burning sensation of the face, throat hands or feet
• Hypotension, worsening of renal (kidney) function or fluid retention
• Gynecomastia/Breast tenderness/increase in breast size/lump under the arm or breast area
• Lack of libido, sexual dysfunction 
• Mental, psychological or cognitive issues (e.g. depression, confusion, memory loss, etc.)
• Severe scalp irritation 

It’s important to closely and regularly monitor for these side effects while taking Finoxidil™, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop using Finoxidil™ and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience:    

• Unwanted hair growth on the face or body (hypertrichosis) 
• Headache    
• Insomnia 
• Nausea 
• Local scalp irritation, including redness or minor swelling
• Hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Some may also experience changes in hair texture and color. 

These are not all the possible side effects of Finoxidil™. For more information, ask your healthcare provider or pharmacist and refer to the complete prescribing information: Finasteride, Topical Minoxidil, Tretinoin, Melatonin

SERIOUS WARNINGS:

• CARDIAC EFFECTS: In rare cases topical minoxidil, one of the active ingredients in Finoxidil™, can lead to cardiovascular side effects. Pericardial effusions, which is the excessive buildup of fluid in the sac surrounding the heart (pericardium), have been reported in patients taking minoxidil. This can progress to cardiac tamponade, which is a life-threatening condition where the fluid pressure compresses the heart, preventing it from effectively pumping blood. Symptoms encompass sharp chest pain and breathing difficulties. If you notice these symptoms, seek immediate emergency medical care. 
• PREGNANCY RISK: Finasteride, one of the active ingredients in Finoxidil™ is a category X teratogenic medication that can cause birth defects in male fetuses. Finasteride should not be used by women who have child-bearing potential. Women who are planning to get pregnant, are pregnant, or breastfeeding must avoid contact with Finasteride. You must not donate blood while on Finasteride to prevent female recipients from being exposed. This medication should not be used or applied around children, other women of childbearing age, and pets.

Do not let children, pregnant or breastfeeding women, or women who may become pregnant handle this medication. Do not let them touch the area where the medication is applied (such as your scalp). If contact occurs, they should immediately wash the affected skin area with soap and water.Always use Finoxidil™under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

WARNING: TOXIC TO PETS  

• Minoxidil, one of the active ingredients in Finoxidil™, is highly toxic to animals, especially cats; even trace amounts can be life-threatening. 
• Do not apply minoxidil if pets are in close proximity
• Do not approach your pets until the treated area has thoroughly dried
• Wash hands and surfaces thoroughly after application
• Do not let pets near the application site (i.e. do not hold pets near your face/hair)
• Beware of pillowcases: minoxidil can transfer to pillow cases during sleep. To prevent any risk to your pets, especially cats, consider removing or replacing pillow cases after use. Alternatively, ensure that your pets do not have access to areas where pillows might be.
• Always store Finoxidil™ in a secure location out of reach of pets. 
• If you suspect your pet has come into contact with minoxidil or displays symptoms such as lethargy, rapid breathing, vomiting, or collapse, seek emergency veterinary care immediately.

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA:  Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Instructions For Use:

• Follow your healthcare provider's specific instructions when using this medication
• Do not apply this medication more than the recommended dose; doing so won't enhance results and may raise the likelihood of side effects
• Wash your hands with soap after application
• This product is meant solely for your scalp, repeated contact with other skin areas can potentially result in unwanted hair growth. If the medication accidentally gets on your face, wash it off with soap and water immediately.
• Do not apply on other parts of the body
• Avoid contact with the eyes. In case of accidental contact, rinse eyes with copious amounts of cool tap water 
• Do not use this medication for a condition for which it was not prescribed.
• Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Storage Information:

• Keep this medication at a room temperature 
• Dispose of the medication if you are no longer using it. 
• Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is not comprehensive. Please see the full prescribing link below for complete safety information: Finasteride, Topical Minoxidil, Tretinoin, Melatonin

You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider.

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about topical Rosemary Plus:

• Rosemary Plus a compounded topical medication combining rosemary oil, cetirizine, caffeine and melatonin.
• Topical Rosemary is sometimes used as an over the counter  treatment for hair loss in certain individuals, particularly in women who have a condition called androgenetic alopecia (female pattern hair loss) or other hair loss conditions with an androgenic component.
• Cetirizine, Caffeine and Melatonin are compounded together to be used off-label as a supportive topical therapy aiding in promoting blood flow, a better scalp environment, preventing further hair loss, and improving hair growth.

Absolute Contraindications – DO NOT use Rosemary Plus if you: 

• Are allergic to any of the active ingredients
• Are under 18 or are pregnant, breastfeeding, or planning to become pregnant 

Drug Interactions – DO NOT use Rosemary Plus if you take: 

• Alfentanil
• Alprazolam
• Buprenorphine
• Opioids
• Certain hepatic/renal medications or medications (see a doctor in-person about seeking treatment with oral Spironolactone)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Feeling faint, shortness of breath, or difficulty breathing 
• Respiratory Depression

It’s important to closely and regularly monitor for these side effects while taking oral Rosemary Plus, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop treatment and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Headache   
• Local scalp irritation, including redness or minor swelling
• Hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Some may also experience changes in hair texture and color. 

These are not all the possible side effects of Rosemary Plus. For more information, ask your healthcare provider or pharmacist and refer to the complete prescribing information at the end of this page.

Always use Rosemary Plus under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Instructions For Use:

• Follow your healthcare provider's specific instructions when using this medication
• Do not apply this medication more than the recommended dose; doing so won't enhance results and may raise the likelihood of side effects
• Wash your hands with soap after application
• This product is meant solely for your sclap, repeated contact with other skin areas can potentially result in unwanted hair growth. If the medication accidentally gets on your face, wash it off with soap and water immediately.
• Do not apply on other parts of the body
• Avoid contact with the eyes. In case of accidental contact, rinse eyes with copious amounts of cool tap water. 
• Do not use this medication for a condition for which it was not prescribed.
• Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Storage Information:

• Keep this medication at a room temperature 
• Dispose of the medication if you are no longer using it. 
• Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

 

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is not comprehensive. Please see the full prescribing link below for complete safety information: Rosemary oil, Cetirizine, Caffeine, Melatonin

You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider.

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about Tangl FOAM: 

•  Tangl FOAM is a compounded topical medication combining 5% topical minoxidil, caffeine and melatonin.
• Topical Minoxidil is a widely used medication for the treatment of hair loss, including androgenetic alopecia. 
• Caffeine & Melatonin are compounded together to be used off-label as a supportive topical therapy aiding in better absorption of the ingredients, an optimized scalp environment, and improving the hair growth cycle.

Absolute Contraindications – DO NOT use Tangl FOAM if you: 

• Are allergic to any of the active ingredients
• Are under 18, or are  pregnant, breastfeeding, or planning to become pregnant
• Have any present or past cancer, heart failure, kidney problems or liver problems (see a doctor in-person about seeking treatment with Tangl FOAM) 

Drug Interactions – DO NOT use Tangl FOAM if you take: 

• Certain blood pressure medications (see a doctor in person about seeking treatment with Tangl FOAM)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Hypotension (low blood pressure) or worsening of renal(kidney) function 
• Fluid retention or swelling in the face, hands, legs, feet or elsewhere
• Feeling faint, shortness of breath, chest pain, or difficulty breathing 
• Severe skin irritation

It’s important to closely and regularly monitor for these side effects while taking Tangl FOAM, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop using Tangl FOAM and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Headache   
• Unwanted hair growth on the face or body
• Hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Some may also experience changes in hair texture and color. 

These are not all the possible side effects of Tangl FOAM. For more information, ask your healthcare provider and refer to the complete prescribing information: Topical Minoxidil, Tretinoin, Melatonin

WARNING: POSSIBLE SERIOUS CARDIAC RISK

In rare cases topical minoxidil, one of the active ingredients in Tangl FOAM can lead to cardiovascular side effects. Pericardial effusions, which is the excessive buildup of fluid in the sac surrounding the heart (pericardium), have been reported in patients taking minoxidil. This can progress to cardiac tamponade, which is a life-threatening condition where the fluid pressure compresses the heart, preventing it from effectively pumping blood. Symptoms encompass sharp chest pain and breathing difficulties. If you notice these symptoms, seek immediate emergency medical care.

Always use Tangl FOAM under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

WARNING: TOXIC TO PETS  

• Minoxidil, one of the active ingredients in Tangl FOAM is highly toxic to animals, especially cats; even trace amounts can be life-threatening. 
• Do not apply minoxidil if pets are in close proximity
• Do not approach your pets until the treated area has thoroughly dried
• Wash hands and surfaces thoroughly after application
• Do not let pets near the application site (i.e. do not hold pets near your face/hair)
• Beware of pillowcases: minoxidil can transfer to pillow cases during sleep. To prevent any risk to your pets, especially cats, consider removing or replacing pillowcases after use. Alternatively, ensure that your pets do not have access to areas where pillows might be.
• Always store Tangl FOAM in a secure location out of reach of pets. 

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Instructions For Use:

• Follow your healthcare provider's specific instructions when using this medication
• Do not apply this medication more than the recommended dose; doing so won't enhance results and may raise the likelihood of side effects
• Wash your hands with soap after application
• This product is meant solely for your scalp, repeated contact with other skin areas can potentially result in unwanted hair growth. If the medication accidentally gets on your face, wash it off with soap and water immediately.
• Do not apply on other parts of the body
• Avoid contact with the eyes. In case of accidental contact, rinse eyes with copious amounts of cool tap water 
• Do not use this medication for a condition for which it was not prescribed.
• Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Storage Information:

• Keep this medication at a room temperature 
• Dispose of the medication if you are no longer using it. 
• Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is not comprehensive. Please see the full prescribing link below for complete safety information: Topical Minoxidil, Tretinoin, Melatonin

You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider.

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about Double Growth Hair Capsules™:

Double Growth is a compounded oral medication combining spironolactone, oral minoxidil, folic acid, vitamin B12 and vitamin D3. 

• Spironolactone is primarily a medication used to treat conditions like high blood pressure and fluid retention (edema) due to its diuretic effects. Spironolactone is sometimes used off-label for its anti-androgenic effects in the treatment of hair loss in women who have a condition called androgenetic alopecia (female pattern hair loss) or other hair loss conditions with an androgenic component. Spironolactone is primarily a medication used to treat conditions like high blood pressure and fluid retention (edema) due to its anti-androgenic effects.
• Oral minoxidil is FDA-approved for high blood pressure treatment for patients unresponsive to other blood pressure treatments. For hair loss, dermatologists may prescribe it “off-label” in low doses. While it has been observed to promote hair growth, its FDA approval and long term safety data is for blood pressure management. 
• Folic acid, vitamin B12 and vitamin D3 are compounded together to be used off-label as a supportive oral therapy aiding in promoting hair follicle health and improving hair growth.

Absolute Contraindications – DO NOT use Double Growth Hair Caps™if you: 

• Are allergic to any of the active ingredients
• Are under 18 or are pregnant, breastfeeding, or planning to become pregnant 
• Have a history of cancer, heart failure, kidney problems or liver problems
• Have any present or past heart conditions like arrhythmias (abnormal heart rhythms), angina (ongoing chest pain), carditis, cardiomyopathy, heart valve disease, stroke, heart attack, congenital heart disease, aortic aneurysms, peripheral artery disease, EKG abnormalities, or other vascular conditions.
• Have high/low blood pressure or orthostatic hypotension
• Have any present or past issues with hyperkalemia, Addison's disease (chronic adrenal insufficiency), or other conditions associated with hyperkalemia and or are receiving other potassium-sparing agents.
• Have any pulmonary, endocrine (thyroid/adrenal), rheumatological (bone/joint) or GI conditions such as pulmonary hypertension, hyperthyroidism, Addison’s disease, pheochromocytoma, lupus, rheumatoid arthritis, osteoarthritis, gastric ulcers, ulcerative colitis, GI bleeding, or other conditions. 

 

Drug Interactions – DO NOT use Double Growth Hair Caps™if you take: 

• ACE inhibitors
• angiotensin receptor blockers
• Potassium channel blockers or medications for hyperkalemia
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Diuretics
• Trimethoprim
• Lithium
• Cholestyramine
• Abiraterone
• Digoxin
• Eplerenone
• Alfentanil
• Alprazolam
• Buprenorphine
• Opioids
• Trimethoprim
• Lithium
• Guanethidine
• Certain blood pressure medications and certain hepatic (liver) medications or medications for Addison’s disease (see a doctor in-person about seeking treatment with Double Growth Hair Caps™)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Chest pain or tightness 
• Shortness of breath or difficulty breathing 
• Rapid heart rate or heart palpitations (irregular heartbeats)  
• Dizziness, lightheadedness or fainting 
• Swelling in the face, hands, legs, feet or ankles 
• Rapid weight gain or fluid retention (edema) 
• Significant or sudden drop in blood pressure (hypotension)
• Worsening of renal (kidney) or hepatic (liver) function 
• Severe skin rashes 
• Digestive abnormalities including severe heartburn/indigestion, vomiting, pain or bleeding 
• Electrolyte and metabolic abnormalities
• Increase in potassium (hyperkalemia)
• Impaired neurological function
• Gynecomastia/breast tenderness/increase in breast size
• Stevens-Johnson Syndrome (SJS)

It’s important to closely and regularly monitor for these side effects while taking Double Growth Hair Caps™, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop taking Double Growth Hair Caps™ and get immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Unwanted hair growth on the face or body (hypertrichosis) 
• Increased urination
• Headache    
• Insomnia or changes in energy levels  
• Nausea 
• Changes in libido and menstrual cycle (e.g. irregular or absence of periods)   
• Hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Some may also experience changes in hair texture and color. 

These are not all the possible side effects of Double Growth Hair Caps™. For more information, ask your healthcare provider or pharmacist and refer to the complete prescribing information: Spironolactone, Oral Minoxidil  

WARNING: SERIOUS CARDIAC EFFECTS

Minoxidil, one of the active ingredients in Double Growth Hair Caps™, can lead to cardiovascular side effects. Pericardial effusions, which is the excessive buildup of fluid in the sac surrounding the heart (pericardium), have been reported in patients taking minoxidil. This can progress to cardiac tamponade, which is a life-threatening condition where the fluid pressure compresses the heart, preventing it from effectively pumping blood. Symptoms encompass sharp chest pain and breathing difficulties. If you notice these symptoms, seek immediate emergency medical care.

Animal testing results: During animal testing, minoxidil was found to cause cardiac lesions and other harmful heart effects. Although animal findings don't always reflect human responses, Tangl dermatologists adhere to a principle of caution when prescribing. Due to its potential cardiac implications you should not use Double Growth Hair Caps™ if you have any heart conditions or a history of cardiac issues. If you notice any cardiac symptoms, seek immediate emergency medical care. 

WARNING: SERIOUS PREGNANCY RISK

Spironolactone, one of the active ingredients in Double Growth™ may cause birth defects based on its mechanism and animal studies. Pregnant women and women who plan to become pregnant in the near future, should not take spironolactone under any circumstances.

WARNING: POSSIBLE INFERTILITY RISK

Spironolactone, one of the active ingredients in Double Growth Hair Caps™ may cause an increased risk of  infertility, breast tenderness/increase in breast size, irregular periods, or lack of menstrual periods. If you notice these symptoms, seek immediate emergency medical care.

WARNING: POSSIBLE CANCER RISK

Spironolactone, one of the active ingredients in Double Growth Hair Caps™, may cause an increased risk of certain types of cancer.  During animal testing, spironolactone caused tumor growth in specific rats. Although animal findings don't always reflect human responses, Tangl dermatologists adhere to a principle of caution when prescribing. Due to its potential carcinogenic implications, you should not use Double Growth Hair Caps™ if you have a history or risk of cancer. If you notice any unusual symptoms, seek immediate emergency medical care. 

Always use Double Growth Hair Caps™ under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

WARNING: TOXIC TO ANIMALS  

• Minoxidil is highly toxic to animals, especially cats; even trace amounts can be life-threatening. 
• Always store minoxidil in a secure location out of reach of pets. 
• If you suspect your pet has come into contact with minoxidil or displays symptoms such as lethargy, rapid breathing, vomiting, or collapse, seek emergency veterinary care immediately.

Always Inform Medical Professionals:

• Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment.
• Minoxidil may cause changes to your EKG; always inform your doctor that you are taking Double Growth Hair Caps™ before an EKG or before starting any new medication. 
• You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

 

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Instructions For Use:

• Follow your healthcare provider's specific instructions when using this medication
• Do not take more than the recommended dose
• Do not use this medication for a condition for which it was not prescribed.
• Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is not comprehensive. Please see the full prescribing link below for complete safety information: Spironolactone, Oral Minoxidil

You must always read this safety information prior to starting this medication and whenever you get a refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider

This product has not been approved by the FDA for hair loss. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about Oral Minoxidil:  

Oral minoxidil is FDA-approved for high blood pressure treatment for patients unresponsive to other blood pressure treatments. For hair loss, dermatologists may prescribe it “off-label” in low doses. While it has been observed to promote hair growth, its FDA approval and long term safety data pertains to blood pressure management.

Absolute Contraindications – DO NOT use oral minoxidil if you: 

• Are allergic to oral minoxidil 
• Are under 18 or haven't completed menopause
• Are pregnant, breastfeeding, or planning a pregnancy 
• Have a history of cancer, heart failure, kidney problems or liver problems
• Have any present or past heart conditions like arrhythmias (abnormal heart rhythms), angina (ongoing chest pain), carditis, cardiomyopathy, heart valve disease, stroke, heart attack, congenital heart disease, aortic aneurysms, peripheral artery disease, EKG abnormalities, or other vascular conditions.
• Have high/low blood pressure or orthostatic hypotension
• Have any pulmonary, endocrine (thyroid/adrenal), rheumatological (bone/joint) or GI conditions such as pulmonary hypertension, hyperthyroidism, Addison’s disease, pheochromocytoma, lupus, rheumatoid arthritis, osteoarthritis, gastric ulcers, ulcerative colitis, GI bleeding, or other conditions. 

Drug Interactions – DO NOT use oral minoxidil if you take: 

• Lithium
• Guanethidine
• Certain blood pressure medications (see a doctor in-person about seeking treatment with oral minoxidil)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Chest pain or tightness 
• Shortness of breath or difficulty breathing 
• Rapid heart rate or heart palpitations (irregular heartbeats)  
• Swelling in the face, hands, legs, feet or ankles 
• Rapid weight gain or fluid retention (edema) 
• Significant or sudden drop in blood pressure
• Dizziness, lightheadedness or fainting 
• Severe skin rashes 
• Vomiting, severe heartburn/indigestion or bleeding 

It’s important to closely and regularly monitor for these side effects while taking oral minoxidil, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any, stop taking oral minoxidil and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Unwanted hair growth on the face or body (hypertrichosis) 
• Headache    
• Insomnia 
• Nausea 
• Hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Some may also experience changes in hair texture and color. 

These are not all of the possible side effects of oral minoxidil. For more information, ask your healthcare provider or pharmacist and refer to the full prescribing information for minoxidil.  

WARNING: SERIOUS CARDIAC EFFECTS
Oral minoxidil can lead to severe cardiovascular side effects. Pericardial effusions, which is the excessive buildup of fluid in the sac surrounding the heart (pericardium), have been reported in patients taking oral minoxidil. This can progress to cardiac tamponade, which is a life-threatening condition where the fluid pressure compresses the heart, preventing it from effectively pumping blood. Symptoms encompass sharp chest pain and breathing difficulties. If you notice these symptoms, seek immediate emergency medical care.

Animal Testing Results: During animal testing, minoxidil was found to cause cardiac lesions and other harmful heart effects. Although animal findings don't always reflect human responses, Tangl dermatologists adhere to a principle of caution when prescribing. Due to its potential cardiac implications and concerns arising from animal studies related to cancer, you should not use oral minoxidil if you have any heart conditions, a history of major cardiac events, or a history and/or risk of cancer. 

Always use oral minoxidil under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

WARNING: TOXIC TO PETS  

• Minoxidil is highly toxic to animals, especially cats; even trace amounts can be life-threatening. 
• Always store minoxidil in a secure location out of reach of pets. 
• If you suspect your pet has come into contact with minoxidil or displays symptoms such as lethargy, rapid breathing, vomiting, or collapse, seek emergency veterinary care immediately.

Always Inform Medical Professionals:

•  Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment.
• Minoxidil may cause changes to your EKG; always inform your doctor that you are taking oral minoxidil before an EKG or before starting any new medication. 
• You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary.

This information is not comprehensive. Please see the full prescribing link below for complete safety information: Oral Minoxidil

You always must review this safety information prior to starting this medication and whenever you get a refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider

This product has not been approved by the FDA for hair loss. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about oral Spironolactone:
Spironolactone is primarily a medication used to treat conditions like high blood pressure and fluid retention (edema) due to its anti-androgenic effects. Oral Spironolactone is sometimes used off-label as a treatment for hair loss in certain individuals, particularly in women who have a condition called androgenetic alopecia (female pattern hair loss) or other hair loss conditions with an androgenic component. While you are taking this medication, you should be cautious of foods that are known to have high potassium levels.

Absolute Contraindications – DO NOT use oral Spironolactone if you: 

• Are allergic to oral Spironolactone
• Are under 18 or are pregnant, breastfeeding, or planning to become pregnant 
• Have a history of cancer, heart failure, kidney problems or liver problems
• Have any present or past issues with hyperkalemia, Addison's disease (chronic adrenal insufficiency), or other conditions associated with hyperkalemia and/or are receiving other potassium-sparing agents.

Drug Interactions – DO NOT use oral Spironolactone if you take: 

• ACE inhibitors
• angiotensin receptor blockers
• Potassium channel blockers or medications for hyperkalemia
• Non-steroidal anti-inflammatory drugs (NSAIDs)
• Diuretics
• Trimethoprim
• Lithium
• Cholestyramine
• Abiraterone
• Digoxin
• Eplerenone
• Certain hepatic/ liver medications or medications for Addison’s disease (see a doctor in-person about seeking treatment with oral Spironolactone)

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Hypotension 
• Worsening of renal (kidney) or hepatic (liver) function
• Digestive abnormalities including bleeding and vomiting 
• Electrolyte and metabolic abnormalities
• Feeling faint, shortness of breath, or difficulty breathing 
• Increase in potassium (hyperkalemia)
• Gynecomastia/breast tenderness/increase in breast size
• Impaired neurological function 
• Stevens-Johnson Syndrome (SJS)

It’s important to closely and regularly monitor for these side effects while taking oral spironolactone, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop taking oral spironolactone and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Headache   
• Increased urination 
• Insomnia or changes in energy levels
• Nausea 
• Changes in libido and menstrual cycle (e.g. irregular or absence of periods)   
• Hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Some may also experience changes in hair texture and color. 

 

These are not all the possible side effects of oral Spironolactone. For more information, ask your healthcare provider or pharmacist and refer to the full prescribing information.

 

SERIOUS WARNINGS:

• PREGNANCY RISK : Spironolactone may cause birth defects based on its mechanism and animal studies. Pregnant women and women who plan to become pregnant in the near future, should not take spironolactone under any circumstances. 
• INFERTILITY RISK: Spironolactone may cause an increased risk of  infertility, breast tenderness/increase in breast size, irregular periods, or lack of menstrual periods. If you notice these symptoms, seek immediate emergency medical care. 
• CANCER RISK: Spironolactone may cause an increased risk of certain types of cancer.  During animal testing, spironolactone caused tumor growth in specific rats. Although animal findings don't always reflect human responses, Tangl dermatologists adhere to a principle of caution when prescribing. Due to its potential carcinogenic implications, you should not use oral Spironolactone if you have a history or risk of cancer. If you notice any unusual symptoms, seek immediate emergency medical care. 

Always use Oral Spironolactone under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary.This information is not comprehensive. Please see the full prescribing link below for complete safety information: Oral Spironolactone

You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider.

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about Tangl BROW: 

• Tangl BROW is a compounded topical medication combining Latanoprost, topical minoxidil, caffeine and melatonin.
• Latanoprost is a medication primarily used for the treatment of glaucoma, an eye condition that causes increased pressure within the eye. There have been some studies and discussions about the potential use of latanoprost for promoting hair growth. The idea emerged from observations that some patients using latanoprost for glaucoma treatment experienced increased eyelash growth as a side effect. This led to its off-label use in treating conditions like alopecia (hair loss).  
• Topical minoxidil is a widely used medication for the treatment of hair loss, including androgenetic alopecia. 
• Caffeine and melatonin are compounded together to be used off-label as a supportive topical therapy aiding in better absorption of the ingredients, an optimized scalp environment, and improving the hair growth cycle.

Absolute Contraindications – DO NOT use Tangl BROW if you: 

• Are allergic to any of the active ingredients
• Are under 18 or are pregnant, breastfeeding, or planning to become pregnant
• Have eye pressure problems, history of intraocular inflammation (uveitis/iritis)
• Have been diagnosed with glaucoma
• Have risk factors for macular edema
• Have been diagnosed with aphakia (no lens in eye) pseudophakia (artificial eye, or a torn posterior lens capsule
• Have any present or past cancer, heart failure, kidney problems or liver problems (see a doctor in-person about seeking treatment with Tangl BROW) 

Drug Interactions – DO NOT use Tangl BROW if you take: 

• Certain blood pressure medications (see a doctor in person about seeking treatment with Tangl BROW)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Hypotension (low blood pressure) or worsening of renal (kidney) function
• Fluid retention or swelling in the face, hands, legs, feet or elsewhere
• Feeling faint, shortness of breath, chest pain, or difficulty breathing 
• Severe skin irritation

It’s important to closely and regularly monitor for these side effects while taking Tangl BROW, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop using Tangl BROW and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Headache   
• Eyebrow irritation, including redness, itching or minor swelling
• Latanoprost has been reported to cause changes to pigmented tissues. The most frequently reported changes have been increased pigmentation of the iris, periorbital tissue (eyelid), and eyelashes. Pigmentation around the skin is expected to increase as long as latanoprost is applied.
• Eyebrow hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Unwanted hair growth on the face or body
• Some may also experience changes in hair texture and color. 

These are not all the possible side effects of Tangl BROW. For more information, ask your healthcare provider or pharmacist and refer to the complete prescribing information: Latanoprost, Topical Minoxidil, Caffeine, Melatonin

WARNING: POSSIBLE CARDIAC RISK
In rare cases topical minoxidil, one of the active ingredients in Tangl BROW can lead to cardiovascular side effects. Pericardial effusions, which is the excessive buildup of fluid in the sac surrounding the heart (pericardium), have been reported in patients taking minoxidil. This can progress to cardiac tamponade, which is a life-threatening condition where the fluid pressure compresses the heart, preventing it from effectively pumping blood. Symptoms encompass sharp chest pain and breathing difficulties. If you notice these symptoms, stop treatment and seek immediate emergency medical care. 

Always use Tangl BROW under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

WARNING: TOXIC TO PETS  

• Minoxidil, one of the active ingredients in Tangl BROW is highly toxic to animals, especially cats; even trace amounts can be life-threatening. 
• Do not apply minoxidil if pets are in close proximity
• Do not approach your pets until the treated area has thoroughly dried
• Wash hands and surfaces thoroughly after application
• Do not let pets near the application site (i.e. do not hold pets near your face/hair)
• Beware of pillowcases: minoxidil can transfer to pillowcases during sleep. To prevent any risk to your pets, especially cats, consider removing or replacing pillowcases after use. Alternatively, ensure that your pets do not have access to areas where pillows might be.
• Always store Tangl BROW in a secure location out of reach of pets. 
• If you suspect your pet has come into contact with minoxidil or displays symptoms such as lethargy, rapid breathing, vomiting, or collapse, seek emergency veterinary care immediately.

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment. 

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Instructions For Use:

• Follow your healthcare provider's specific instructions when using this medication
• Do not apply this medication more than the recommended dose; doing so won't enhance results and may raise the likelihood of side effects
• Wash your hands with soap after application
• This product is meant solely for your eyebrows, repeated contact with other skin areas can potentially result in unwanted hair growth. If the medication accidentally gets on your face, wash it off with soap and water immediately.
• Do not apply on other parts of the body
• Avoid contact with the eyes. In case of accidental contact, rinse eyes with copious amounts of cool tap water 
• Do not use this medication for a condition for which it was not prescribed.
• Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Storage Information

• Keep this medication at a room temperature 
• Dispose of the medication if you are no longer using it. 
• Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary.This information is not comprehensive. Please see the full prescribing link below for complete safety information: Latanoprost, Topical Minoxidil, Caffeine, Melatonin

You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider.

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about Tangl LASH (generic Latisse®):

Bimatoprost, the active ingredient in Tangl LASH (generic Latisse®), is a medication that was originally developed for the treatment of glaucoma, an eye condition characterized by increased intraocular pressure that can damage the optic nerve and lead to vision loss. However, similar to latanoprost, bimatoprost has also been investigated for its potential to promote hair growth, particularly in cases of androgenic alopecia (male and female pattern baldness). In the context of hair growth, bimatoprost is thought to influence the prostaglandin pathway, which can affect hair follicle activity and cycling.

Absolute Contraindications – DO NOT Tangl LASH (generic Latisse®) if you: 

• Are allergic to any of the active ingredients
• If you are pregnant, breastfeeding, or planning to become pregnant.
• Have eye pressure problems, intraocular pressure (IOP), or a history of IOP
• Have been diagnosed with glaucoma
• Have risk factors for macular edema
• Have been diagnosed with aphakia (no lens in eye) pseudophakia (artificial eye, or a torn posterior lens capsule

Drug Interactions – DO NOT Tangl LASH (generic Latisse®) if you take: 

• Certain ocular (eye) related medications (see a doctor in person about seeking treatment with Tangl LASH)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Color Change of Iris
• Vision Changes
• Macular Edema

It’s important to closely and regularly monitor for these side effects while taking Tangl LASH (generic Latisse®), especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop taking the medication and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Eye sensitivity/ interaction with contacts
• Eye Inflammation
• Eyelash shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Some may also experience changes in hair texture and color. 

These are not all the possible side effects of Tangl LASH (generic Latisse®). For more information, ask your healthcare provider or pharmacist and refer to the complete prescribing information: Bimatoprost

Always use Tangl LASH (generic Latisse®) under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.

Instructions For Use:

• Follow your healthcare provider's specific instructions when using this medication
• Do not apply this medication more than the recommended dose; doing so won't enhance results and may raise the likelihood of side effects
• Wash your hands with soap after application
• This product is meant solely for your eye lashes, repeated contact with other skin areas can potentially result in unwanted hair growth. If the medication accidentally gets on your face, wash it off with soap and water immediately.
• Do not apply on other parts of the body
• Avoid contact with the eyes. In case of accidental contact, rinse eyes with copious amounts of cool tap water 
• Do not use this medication for a condition for which it was not prescribed.
• Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Storage Information:

• Keep this medication at a room temperature 
• Dispose of the medication if you are no longer using it. 
• Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is not comprehensive. Please see the full prescribing link below for complete safety information: Bimatoprost

You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider.

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about topical Tangl NAIL: 

Tangl NAIL is a compounded topical medication combining itraconazole, fluconazole, terbinafine, ibuprofen, and tea tree oil, compounded together as an off-label topical therapy aiding in promoting a healthy nail matrix, elimination of fungal spores and membranes and preventing further pathological thickening of the nail bed.

• Itraconazole is an antifungal medication commonly used to treat nail fungus infections, a condition known as onychomycosis. It belongs to a class of drugs called triazole antifungals. Itraconazole works by inhibiting the synthesis of ergosterol, a crucial component of fungal cells. By inhibiting squalene epoxidase, terbinafine disrupts the synthesis of ergosterol. Without sufficient ergosterol, fungal cell membranes become structurally unstable and more permeable. Additionally, the accumulation of toxic squalene and other intermediates within the fungal cells further disrupts the integrity and function of the cell membrane. 
• Fluconazole interferes with the activity of certain enzymes known as cytochrome P450 enzymes that are involved in the synthesis of ergosterol, a key component of fungal cell membranes. These enzymes are part of the ergosterol biosynthesis pathway, similar to the way they are targeted by other azole antifungal medications. 
• Terbinafine targets an enzyme called squalene epoxidase, which is a key enzyme in the fungal ergosterol biosynthesis pathway. Ergosterol is a vital component of fungal cell membranes, similar to cholesterol in human cell membranes.
• Ibuprofen acts on isolated dermatophytes may related to the inhibitory action of on-secreted COX that is produced by fungal cells and not to direct toxicity that NSAIDs may have. Inhibition of prostaglandin production is not the only mechanism of ibuprofen in fungal cells.
• Tea tree oil contains compounds called terpenes, with terpinen-4-ol being the most well-known and active component. Terpinen-4-ol is believed to have antifungal activity by disrupting the structure and function of fungal cell membranes. It may interfere with fungal enzymes and proteins, leading to the inhibition of fungal growth and proliferation.

Absolute Contraindications – DO NOT use Tangl NAIL if you: 

• Are allergic to any of the active ingredients
• Are under 18 or are pregnant, breastfeeding, or planning to become pregnant 

Drug Interactions – DO NOT use Tangl NAIL if you take: 

• Certain cytochrome 450 related medications (see a doctor in-person about seeking treatment with Tangl NAIL if this applies to you)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you:  

• Develop skin blisters (dermal vesicles)

It’s important to closely and regularly monitor for these side effects while applying Tangl NAIL, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop taking Tangl NAIL and seek immediate medical attention, or call 911.  

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Ingrown toenails
• Application site pain
• Dermatitis

These are not all the possible side effects of Tangl NAIL For more information, ask your healthcare provider or pharmacist and refer to the complete prescribing information: Itraconazole,  Fluconazole, Terbinafine, Ibuprofen

Always use Tangl NAIL under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch or call 1-800-FDA-1088.

Instructions For Use:

• Follow your healthcare provider's specific instructions when using this medication
• Do not apply this medication more than the recommended dose; doing so won't enhance results and may raise the likelihood of side effects
• Wash your hands with soap after application
• This product is meant solely for your toenails, repeated contact with other skin areas can potentially result in unwanted skin irritation
• Do not apply on other parts of the body
• Avoid contact with the eyes. In case of accidental contact, rinse eyes with copious amounts of cool tap water 
• Do not use this medication for a condition for which it was not prescribed.
• Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Storage Information

• Keep this medication at a room temperature 
• Dispose of the medication if you are no longer using it. 
• Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is not comprehensive. Please see the full prescribing link below for complete safety information: Itraconazole, Fluconazole, Terbinafine, Ibuprofen