Minoxidil Plus

Drug Safety Information

You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider.

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about Tangl FOAM: 

•  Tangl FOAM is a compounded topical medication combining 5% topical minoxidil, caffeine and melatonin.
• Topical Minoxidil is a widely used medication for the treatment of hair loss, including androgenetic alopecia. 
• Caffeine & Melatonin are compounded together to be used off-label as a supportive topical therapy aiding in better absorption of the ingredients, an optimized scalp environment, and improving the hair growth cycle.

Absolute Contraindications – DO NOT use Tangl FOAM if you: 

• Are allergic to any of the active ingredients
• Are under 18, or are  pregnant, breastfeeding, or planning to become pregnant
• Have any present or past cancer, heart failure, kidney problems or liver problems (see a doctor in-person about seeking treatment with Tangl FOAM) 

Drug Interactions – DO NOT use Tangl FOAM if you take: 

• Certain blood pressure medications (see a doctor in person about seeking treatment with Tangl FOAM)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

• Hypotension (low blood pressure) or worsening of renal(kidney) function 
• Fluid retention or swelling in the face, hands, legs, feet or elsewhere
• Feeling faint, shortness of breath, chest pain, or difficulty breathing 
• Severe skin irritation

It’s important to closely and regularly monitor for these side effects while taking Tangl FOAM, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop using Tangl FOAM and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

• Headache   
• Unwanted hair growth on the face or body
• Hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
• Some may also experience changes in hair texture and color. 

These are not all the possible side effects of Tangl FOAM. For more information, ask your healthcare provider and refer to the complete prescribing information: Topical Minoxidil, Tretinoin, Melatonin

WARNING: POSSIBLE SERIOUS CARDIAC RISK

In rare cases topical minoxidil, one of the active ingredients in Tangl FOAM can lead to cardiovascular side effects. Pericardial effusions, which is the excessive buildup of fluid in the sac surrounding the heart (pericardium), have been reported in patients taking minoxidil. This can progress to cardiac tamponade, which is a life-threatening condition where the fluid pressure compresses the heart, preventing it from effectively pumping blood. Symptoms encompass sharp chest pain and breathing difficulties. If you notice these symptoms, seek immediate emergency medical care.

Always use Tangl FOAM under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

WARNING: TOXIC TO PETS  

• Minoxidil, one of the active ingredients in Tangl FOAM is highly toxic to animals, especially cats; even trace amounts can be life-threatening. 
• Do not apply minoxidil if pets are in close proximity
• Do not approach your pets until the treated area has thoroughly dried
• Wash hands and surfaces thoroughly after application
• Do not let pets near the application site (i.e. do not hold pets near your face/hair)
• Beware of pillowcases: minoxidil can transfer to pillow cases during sleep. To prevent any risk to your pets, especially cats, consider removing or replacing pillowcases after use. Alternatively, ensure that your pets do not have access to areas where pillows might be.
• Always store Tangl FOAM in a secure location out of reach of pets. 

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Instructions For Use:

• Follow your healthcare provider's specific instructions when using this medication
• Do not apply this medication more than the recommended dose; doing so won't enhance results and may raise the likelihood of side effects
• Wash your hands with soap after application
• This product is meant solely for your scalp, repeated contact with other skin areas can potentially result in unwanted hair growth. If the medication accidentally gets on your face, wash it off with soap and water immediately.
• Do not apply on other parts of the body
• Avoid contact with the eyes. In case of accidental contact, rinse eyes with copious amounts of cool tap water 
• Do not use this medication for a condition for which it was not prescribed.
• Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Storage Information:

• Keep this medication at a room temperature 
• Dispose of the medication if you are no longer using it. 
• Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is not comprehensive. Please see the full prescribing link below for complete safety information: Topical Minoxidil, Tretinoin, Melatonin