Rx Safety Information - Rx Rosemary Plus

You must always read this safety information before starting this medication and with every refill. There may be new information. This information is not a substitute for discussing your medical condition or treatment with your healthcare provider.

This compounded product has not been approved by the FDA. It is only available if prescribed by a dermatologist  through Tangl who will determine if treatment is suitable. 

What I need to know about topical Rosemary Plus:

  • Rosemary Plus is a compounded topical medication combining rosemary oil, cetirizine, caffeine and melatonin.
  • Topical Rosemary is sometimes used as an over the counter  treatment for hair loss in certain individuals, particularly in women who have a condition called androgenetic alopecia (female pattern hair loss) or other hair loss conditions with an androgenic component.
  • Cetirizine, Caffeine and Melatonin are compounded together to be used off-label as a supportive topical therapy aiding in promoting blood flow, a better scalp environment, preventing further hair loss, and improving hair growth.

Absolute Contraindications – DO NOT use Rosemary Plus if you

  • Are allergic to any of the active ingredients
  • Are under 18 or are pregnant, breastfeeding, or planning to become pregnant 


Drug Interactions – DO NOT use Rosemary Plus if you take: 

  • Alfentanil
  • Alprazolam
  • Buprenorphine
  • Opioids
  • Certain hepatic/renal medications or medications (see a doctor in-person about seeking treatment with oral Spironolactone)  

Serious Side Effects – STOP treatment and seek emergency medical care or call 911 if you experience:  

  • Feeling faint, shortness of breath, or difficulty breathing 
  • Respiratory Depression


It’s important to closely and regularly monitor for these side effects while taking oral Rosemary Plus, especially when starting or changing your dose, as they can indicate a severe reaction. If you notice any side effects, stop treatment and seek immediate medical attention, or call 911. 

Common Side Effects  – Talk to your provider about changing your dose/treatment if you experience: 

  • Headache   
  • Local scalp irritation, including redness or minor swelling
  • Hair shedding: It's common to experience increased hair shedding initially. This is typically a temporary phase as hair follicles regenerate. 
  • Some may also experience changes in hair texture and color. 

These are not all the possible side effects of Rosemary Plus. For more information, ask your healthcare provider or pharmacist and refer to the complete prescribing information at the end of this page.

Always use Rosemary Plus under the supervision of a healthcare professional and undergo regular medical assessments during treatment.

Always Inform Medical Professionals: Always consult a healthcare provider immediately about any unusual side effects, concerns or changes noticed during treatment. You can message your Tangl dermatologist through your Tangl account (trytangl.com/account) if you have any questions or concerns about your treatment.  

Always Provide Accurate Health Information: Failing to provide accurate information about your health and medical history can lead to severe consequences, including harm or, in some instances, death.

Report Side Effects to the FDA: Negative side effects should be reported to the FDA at www.fda.gov/medwatch  or call 1-800-FDA-1088.

Instructions For Use:

  • Follow your healthcare provider's specific instructions when using this medication
  • Do not apply this medication more than the recommended dose; doing so won't enhance results and may raise the likelihood of side effects
  • Wash your hands with soap after application
  • This product is meant solely for your sclap, repeated contact with other skin areas can potentially result in unwanted hair growth. If the medication accidentally gets on your face, wash it off with soap and water immediately.
  • Do not apply on other parts of the body
  • Avoid contact with the eyes. In case of accidental contact, rinse eyes with copious amounts of cool tap water. 
  • Do not use this medication for a condition for which it was not prescribed.
  • Never share this medication with others, even if their symptoms are similar to yours. It may be harmful to them. 

Storage Information:

  • Keep this medication at a room temperature 
  • Dispose of the medication if you are no longer using it. 
  • Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center right away.

Disclaimer: The FDA has not evaluated all the claims made here. This medication is not guaranteed to diagnose, treat, cure, or prevent any disease. Individual results may vary. This information is not comprehensive. Please see the full prescribing link below for complete safety information: Rosemary oil, Cetirizine, Caffeine, Melatonin